Influence of Lavandula angustifolia, Melissa officinalis and Vitex angus-castus on the organism of rats fed with excessive fat-containing diet

Plant food additives are becoming more and popular broadly applied products, though the information on risks they poses to organism is limited contradictive. Obesity overeating some of commonest health issues around world, people increasingly consuming workability-enhancing preparations as a simple fast method weight control. The plant-based considered less harmful than synthetic chemical ones. Lavandula angustifolia Mill., Melissa officinalis L. Vitex angus-castus used medicinal plants, despite fact that their complex physiological assessment model animals in conditions obesity has not yet been performed. We carried out 30-day experiment white male rats. All were given high-fat diet, experimental animals, addition this received 5% crumbled dry herbs angustifolia, M. or V. angus-castus. Taking into account overall amount consumed food, mean daily gain body weight; at end experiment, we determined index internal organs, biochemical morphological blood parameters. At beginning rats examined for motor orienting activities, emotional status. Rats diet gained up 112% by while had 119%, – 135%, 139%, compared with initial weight. Addition plants led increase average increment, significantly reliably after lavender lemon balm, unreliably eating Vitex. reduced relative brain weight, ingestion caused notable decrease mass thymus (down 58% 47% control group respectively). Also, these decreased activities experiment. As parameters blood, activity alkaline phosphatase increased 406% following consumption Melissa, 350% lavender, Vitex, group. Furthermore, all groups observed have AST ALT activities. Intake increases cholesterol (to 125%) LDL 228%), whereas balm decreases urea nitrogen 79%), totalbilirubin 63%) triglycerides 63%). aterogenecity against background fall HDL 52% group). also contributed normalization glucose level. Morphological analysis revealed no significant changes, except heightened content monocytes which characteristic groups, including Effects excessive-fat require additional histological, histochemical immunological surveys.